Pain-Relieving Raw White Crystal Or Powder Phenacetin / Acetophenetidin

Short Description:

Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada,
owing to the similar physical features of the two drugs.
Due to low cost phenacetin is used for research into the physical and refractive properties of crystals.
It is an ideal compound for this type of research.


  • Min.Order Quantity: 10g
  • Supply Ability: 1000kgs/month
  • Port: Shenzhen
  • Payment Terms: Western union, MoneyGram, T/T
  • Product Detail

    Product Tags

    Phenacetin

     

    Properties

    Melting point: 133-136 °C(lit.)

    Boiling point: 132 °C / 4mmHg

    Flash point: 2℃

    storage temp. 2-8°C

    form powder

    color White

    Water Solubility 0.076 g/100 mL

    Sensitive Hygroscopic

    Merck 14,7204

    BRN 1869238

    Stability: Stable. Incompatible with strong oxidizing agents, strong acids.

    InChIKey CPJSUEIXXCENMM-UHFFFAOYSA-N

    Safety Information

    Symbol(GHS)


    Abstract

    Phenacetin is a human carcinogen based on sufficient evidence of carcinogenicity studies in experimental animals. In an 18-month carcinogenicity study, dietary administration of 2.5% phenacetin induced renal cell carcinomas of the renal pelvis and transitional cell carcinomas of the urinary bladder in rats, the tumor incidence in males being greater than in females. In another long-term carcinogenicity study, dietary administration of 0.535% phenacetin for 117 weeks induced renal pelvic tumors in male rats. In B6C3F1 mice of each sex maintained on a diet containing 1.25% or 0.6% phenacetin for 96 weeks, a dose-related induction of renal tumors was observed in male mice, and urinary bladder proliferative lesions developed in mice of either sex fed 1.25% phenacetin.

    Specification

    TEST ITEMS SPECIFICATION RESULTS
    Characters A white or almost white crystalline powder A white crystalline powder
    Identification Infrared absorption spectrum of the substance is same as that of Lidocaine Intermediate CRS Conforms
    Clarity and color of the solution Clear and colorless≤Y6 Conforms
    PH Dissolve 2.0g in water and dilute to 20ml ph 3.5~5.5 4.3
    Optical rotation 4%(W/V)Water solution +135°~+150° +140°
    Heavy metal ≤5ppm <5ppm
    Sulphated ash ≤0.5% 0.02%
    Water content 3.1~4.6% 4.1%
    Acetone ≤0.5% 0.04%
    Butyl alcohol ≤0.5% 0.004%
    Bacterial endotoxins ≤0.5 CFU/g <0.5 CFU/g0.5 CFU/g
    Assay 89.5%~102.0% 95.9%
    B of Lidocaine≤5.0% 5.0
    Conclusion The specification conform with enterprise standard

    More About

    Phenacetin was used as an analgesic and fever-reducing drug in both human and veterinary medicine for many years. It was introduced into therapy in 1887 and was extensively used in analgesic mixtures until it was implicated in kidney disease (nephropathy) due to abuse of analgesics. Phenacetin also was once used as a stabilizer for hydrogen peroxide in hair-bleaching preparations.

    Function

    Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin,

    low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic
    effect. Because the enzyme inhibitor make phenacetins-Acetate not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The mild phenacetins-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.


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